منابع مشابه
Network structure from rich but noisy data
The recent growth in interest in the physics and mathematics of networks has been driven in large part by the increasing availability of data describing the structure of networks ranging from the internet and the web to social and biological networks. It is a surprising feature of many empirical studies, however, that the data are reported without any estimate of their expected accuracy, even t...
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Methylated and un-methylated control DNA is an important part of DNA methylation studies. Although human and mouse DNA methylation control sets are commercially available, in case of methylation studies on other species such as animals, plants, and bacteria, control sets need to be prepared. In this paper a simple method of generating methylated and un-methylated control DNA is described. Whole...
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Attribute noise can affect classification learning. Previous work in handling attribute noise has focused on those predictable attributes that can be predicted by the class and other attributes. However, attributes can often be predictive but unpredictable. Being predictive, they are essential to classification learning and it is important to handle their noise. Being unpredictable, they requir...
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AID/APOBEC family enzymes are best known for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence preferences that can produce mutational signatures in targets such as retroviral and cancer cell genomes. These deaminases have also been proposed to function in DNA demethylation via deamination of either 5-methylcytosine (mC) or TET-oxidized mC bases (ox-mCs),...
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Autoantibodies can be either harmful or beneficial to the body. The beneficial autoantibodies play important roles in immunosurveillance, clearance of body waste and maintenance of immune homeostasis. Despite their importance, however, people's knowledge on the protective autoantibodies is still very limited. In the current study, we examined two autoantibodies that recognized epitopes with onl...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2000
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20000518-02